Example of Disorders of Pigment Epithelium

A number of conditions affect Receptor cells as well as the Pigment Epithelium.Included amongst these are:

  • Retinitis Pigmentosa
  • Cone dystrophy
  • Choroideraemia¬†

These will be discussed in disorders of the Receptor cells.

  • Vitelliform Macular Dystrophy (Best's Disease) affects Pigment Epithelium specifically without involving other retinal layers.

Retinal Pigment Epithelium Disorder

Mother and son

Right Egg yolk -vitelliform Left "Scrambled"
Multifocal ERG

Reduced central responses normal peripheral amplitudes and waveforms

Summary of Best's Dystrophy